I shot a huge doe at 151 yards the other day and got a pass through with the point of inpact going through the shoulder and making a mess and exiting aroung the last rib. Did a great job, she still ran about 120 yards and hopped a fence to my suprise but I blame a lot of that on the distance I shot her at and the loss of energy at that range I guess. I have shot several deer with the Barnes Expander/Knight Red Hot 300 grain bullet and as good as the PB did, the Red Hot is by far the most destructive bullet i have ever used on deer. I killed a 6 point last year and it looked like you had spraygunned blood on the trees the entire 25 yards it went.