I hit a bull moose square in the brisket with my 30-06 using Sierra 180 gr Game King bullet at about 200 yards. He lurched backward and ambled off only about 50 yards and stood broadside where I then hit him twice more through both lungs and he fell in 20 yards.
Upon examining the first bullet path it hit hit just left of center, took out the left lung and lodged about midbody in the left backstrap. That bullet penetrated 24"-30" through some tough cartlidge and muscle.