I load up 220gr RN for Moose medicine Uncle. Good out to 200 yards with that pill out of my .06. Only reason I limit it to that range is that My Barrel really doesn't like it that well and the groups open up to 1 1/4" or so so I zero at 100. With the best load that my barrel wouldn't show pressure signs from I was only 1" low at 200. I could probably go out to 400 and find it trustworthy but with it grouping a little fishy I just don't have the faith in it. Not to mention it's a VERY rare thing I can't get closer than 200 anyway where I hunt. Hell Most shots are within 100.