The .408 cheytac has 8,295 ft-lbf and 3,500 fps with a 305 gr bullet. The 416 ruger is 5,545 ft-lbf and 2,500 fps with a 400 gr bullet. The ruger will be a cheaper rifle and ammo and components are easier to get and cheaper, and the rifle will weighs less. If you don't only ever rifle I would consider a 375 H&H as ammo and components are ever where brown bears are. My source is from cartridges of the world 13th edition.