"Best for medium game like Coyotes?"
Coyotes are not considered "medium" size game (normally thin skinned smaller hoofed animals).
Coyotes are considered varmint, now more often called "predators".
A .22-250 is an excellent caliber/cartridge for animals under +/-75lbs (or more) at +/-300-500 yards (or more).
Lastly, there was a time when the.308 was considered a "long range" caliber/cartridge (now it's a .338 Laupa).
BTW - You're in the ballpark thought - couple nice gun too !!!
Last edited by Sheridan; 12-10-2014 at 08:23 PM.