What'd I tell you before?
For double shoulders with standard bullets stay with 180s in the 06 or 160s in the 7-08.
For double shoulders with premium bullets or ESPECIALLY with monos like the Barnes, 130-150s in the 06 & 120-140s in 7-08 are fine.
The only "danger" of a 150 lead core thru the shoulder joint is it not penetrating both lungs. A deer can make 150-200yds on 1 lung. He'll still die but the blood trail may or may not be easy to follow. THAT is why I want a 200% chance of an exit EVERYTIME!