The only ways to get a sure DRT shot is a double shoulder shot (which ruins plenty of meat) or a spine or head shots (which are iffy at best, and most hunters should not try.)
Every now and then a double lung shot deer will drop, not often.
I also like a good exit wound for tracking. I have had two deer that were very hard to find, the reasoning was NOT the bullet, but a high double lunger with small exits. These deer did not go any farther than others did, they just bled out internally! As RR said, deer are not that hard to kill. Interlocks, Partitioners and good old Core-Locts work just fine.
Just stay away from frangible bullets and bullets designed for 1000 lb. animals, neither will work well for whitetail sized animals.