Any place that is vital would be a good place to put the bullet. Deer ain't bulletproof and the Hornady is a fine bullet for deer. The range has absolutely nothing to do with it. Put a Hornady into the vital area and you can get the skinning knife ready. I can't even begin to count the number of game animals I've put down with a 162 gr Hornady BTSP out of my 7mm Mag at ranges up to 400 yards.