I used the Hornady 265 gr. bullets for the first time this season with great results. I took three deer this past weekend, all shot broadside behind the shoulders. The bullets made a complete pass thru on all, and other than making a half dollar size hole both entrance and exit in the ribs, did not damage any of the meat. My hunting buddy used 240 gr. Speer bullets I believe, and although he shot his deer behind the shoulder as well, the bullet did not hold together and did quite a bit of damage. He is changing to the Hornady bullets.