The Accubonds are really good deer bullets. It has been my experience that the TSX needs much higher velocity to expand consistently. The TTSX seems to open better at lower velocities than the TSX. At .280 or 7-08 velocities a softer bullet would probably be a better choice for deer sized game. Most of my current .280 loads are with Accubonds.
Both bullets you mentioned can be very accurate if your rifle likes them. The TSX loads that I have used have been very sensitive as to OAL and needed to be kept further back from the lands than usual to shoot well.