There may be another reason for this accuracy difference: You are shooting a substantially different velocity load with 110 gr T7 loose than 2x50 pellet.

Hogdon data shows 1763 fps for 2-50 pellets. For the same velocity, their data produces 88.0 gr with T72f and 81.4 with T73f. 110 gr. T73f is 214 fps higher, at 1977.

In my shooting, I've found that accuracy sweet spots are about the same with different powders when I use an amount of powder that produces about the same velocity.

Depending on whether you are using 2f or 3f, I suggest you try a load of either about 81 or 88.

See the attached graph, that shows all of this.

Bill