I have hammered deer with everything from 218 bee to 458 Winchester for years. The bee was a neck shot. The rest were either head or behind the shoulder. The only time that you are going to get excessive damage is if you hit high or hit the shoulder directly. Place it a couple inches behind the shoulder on a broadside, and the only thing you are going to wreck is lungs and ribs, and I don't really care if I blow them apart. Moose, elk and bear the same, leaving the 218 out of the equation. My 270 is 400 to 500 fps faster than your 270 Winchester, and if I load a light jacketed bullet it will blow a football sized hole through the ribs and totally vaporize the lungs liver heart and everything else in between. I shot a little forward on a moose with a 375 H&H with a 300 grain and it destroyed a shoulder completely. There was bone fragments everywhere, and the bloodshot area was immense. Put them a little further back, or take a neck shot.