Loose powder, load development and you should be good to go for 200yds shots. Further that it is possible but you will need range time....
BTW, mon MHC shoots moa with
.40 200grSST, 115gr BH209, W209
.45 250grSST, 110gr BH209, W209
.45 300grMZ, 100gr BH209, W209
Good luck