any powder you use is temp sensitive, some a little, some a lot, depending on its makeup, read the lable, if it contains nitrocellulose and nitroglycerine it is a double base or ball powder and is more temp sensitive than a single base powder. RE22 is a double base powder, and the tmp sensitivity I can deal with, what turned me against it was the lot to lot variences, I had the same load in my 6.5 gibbs go from 3360 fp to 3180 just by changing lot numbers on the powder, I'm not gonna rework my load every new lot of powder, If I were you I would try either H1000 or Retumbo.
RR