I use a 41 Ruger new model BlackHawk I shoot a 175 grn silver tip hollow point and It is very comfortable to shoot , it will take down anything n the north American continent.
Good luck , in my opinion a 357 will also work as a backup sidearm I have taken down many big hogs and 1 deer with my mod 28 4 " bbl 357 mag,
bullet placement is the ticket, no matter how big a slug you sling if you are not on target you will not kill.