PowerBelts will kill deer...I've killed dozens with roundballs which are very inefficient...
But, if I'm going to use an inline, with a scope...I'm not going to use a bullet because it's easy to load and you can load a second shot without cleaning the barrel...
I'm planning to use a bullet that is more aerodynamic and will penetrate and mushroom...That will be a bullet designed to be used for hunting from a pistol, in my case, I prefer .44 and .45 caliber pistol bullets...They are designed to be used at similar velocities as muzzleloaders and when matched with the proper sabot and powder charge they are lethal and accurate...