I used to do some deer hunting with a revolver in my native CO. Mine was a Ruger single action in 41 Mag. It would put them down if I did my job right and directed the bullets properly. I traded that pistol and a bunch of others off years ago on a double rifle.

My current pistol for hunting deer is one of the older T/C Contenders. I've got 3 barrels for it, 357 mag, 45 Long Colt/410 and a 7mm TCU. I haven't shot any deer with the 357 Mag barrel but the 45 Long Colt has dropped a few. Mostly I use the 7mm TCU. I topped it with a Leupold 2x pistol scope and use a handloaded 120 Gr Nosler BT bullet. It has proven quite effective on deer and I intend on trying it on pronghorn in the next year or 2.

On a side note, hunting bunnies with the 410 barrel is a lot of fun too.