I actually killed an elk last year and this year both with the 460 gr Lee 500 S&W bullet. Like DC said I Paper Patch them. I use an over powder wad and 80 gr of pyrodex P. I have shot those NE bullets and they shoot very well with 80 gr of pyrodex P and an over powder wad.
The Lee 500 S&W bullet lays the law down on elk or anything smaller. Ron