My daughter hunts with me in SE Alabama. I've loaded both the 100 gr. Partition and 100 gr. Grand Slam for her rifle. Both have done fine. With either of these, a well located shot placement has resulted in a relatively easy recovery ---- 100 yards or less. I like these style bullets because they will plow through a shoulder with ease and seldom fragment. She's only made one poor shot placement and we found it with the help of my tracking pooch.
Some folks lament at a deer running that far, but I don't sweat deer being able to make it 100 +/- yards after being well hit. I have double lunged deer with a 200 gr. out of a 300 Win. Mag. and watched them run 50 -75 yards. And like many of us, several times the deer just flop down dead in their tracks. Truth is that a deer in high gear can be moving around 30 mph, and can make it a good ways in the 5-10 seconds that it takes before the blood pressure drops to where it can no longer stay up.