I'm a big fan of the 375H&H myself. If Africa is in your sights, the 375 Holland would be an ideal choice. The Ruger may be a little harder to find ammo for overseas. I'm told the 375's recoil is a bit more tolerable than the 338, to which I've never shot the latter. Either caliber is much more versatile than the naysayers will tell you. If you reload, skies the limit on what you can do with them. As for guns, I'm a CRF fan, so the Remington 798(Zastava 98 mauser), Win m70, and CZ550 are on the short list. CZ is a bit heavy IMO for a 375, while the Zastava action(found under a slew of names over the years) is the lightest I would consider(I own a 798 in 375). Nothing really wrong with a pushfeed action, however I prefer the robustness of the CRF action with a better extraction and ejection design.