A large coyote will weigh approximately 40 lbs so any 22 centerfire will have plenty of power for them at most ranges.For very long distances the 243' s and 257' s offer more than enough power for coyotes.I have killed 300lb plus deer at distances of over 400 yards with the 25-06 and 257wby and there was more than enough energy to do the job, so while the 270 works well it really is not necessary for any deer hunting as my earlier post stated.Some people use the large 300 magnums for deer but they certainly are not required for deer hunting.For elk , moose or larger bears the 7mms shoot just as flat and offer heavier bullets than the 270.Feel free to use whatever you want as many people (myself included) use cartridges that are overpowered for the game that they hunt.The fact these larger cartridges are used however does not mean that they are at all required and in some cases they are not even desireable for most hunters.