I have been using Federal Vital Shok with Barnes 180 gr TSX for many years on northern whitetails in New England, mule deer and elk in the west. Best factory load IMO available and they shoot equally well through both of my 06's. I understand that Barnes was bought out by the holding company that owns Remington and that they pulled the TSX from the federal lineup. I'll try the equivalent bullet from Remington now and see how it compares with the federal. the TSX is the best shooting and performing bullet I have ever used so I want to continue with that.