On the subject of muzzle loading. You could always load a 50 caliber mini, maxi, or round ball with pryodex or black powder into a 28ga shell and fire it. Or you could put a 54 caliber projectile down the barrel, basically make an inline muzzle loader. As said accuracy is the issue not power. One of the loads I mentioned earlier is basically a 50 caliber round ball going at 2000fps. If this load was coming from a muzzle loader no one would be questioning its effectiveness at bagging deer.