I echo a few others.

Get to a reputable pro shop. Shoot and handle as many "sample" bows as they will let you. Fit, feel, balance, etc. is more or less an individual thing. And in my book necessary for the shooter to be as accurate as he/she can be. These days there are so many well made, lightning fast, durable compound bows that I cannot see how you can go wrong. The compounds I have shot over the past 3 or so decades have included Pearson, Bear, High Country (shot competitively for a few years), PSE, Hoyt and Mathews. All shot great and performed without a flaw except one particular PSE that had one limb split. After something like 80 bazillion shots. My personal favorite was my last - a Mathews SQ2.

As for a hunhting set up, my advice is to keep it as simple as you can. I was not a fan of complicated rests, complex sight systems or mechanical broadheads. A simple durable drop away rest, a fixed 2-3 pin fiber optic sight ... and a quality fixed or replaceable blade broadhead were my cup of tea. Not much that could go wrong.