I've used my 17cal on several fox's and was amazed at how much damage that little 17gr bullet could do. The only draw back for me was any little bit of wind would push the bullet off at distance's over 50yds or so, but it's definately my favorite small caliber round for varmits and pond turtles. Just didn't know how it would perform on yotes, especially on a shot that's not well placed.

As far as cost of ammo, I usually buy Hornady just because they seem to be resonably priced and consistant in performance. Not sayin thier the best, just my choice.

I've been shooting the H-day steel match ammo in my Mossberg 223 and my Ruger mini14for the last few months. My cost has been around $22/box of 50 or .44/round. The last box of H-day 50gr Varmit Express I bought for my 22-250 was $24.5/box of 20 or
$1.22/round. I like the 22-250 for yotes and I really don't think there's much difference in performance b/t the two, I just prefer my 223 b/c the ammo's cheaper which means I can shoot (plinkin) more with the 223.