My Douglas 50cal barrel is tight with a 325gr FTX and the MMP Orange. Its way too tight with the Harvester Black Crushrib. A $20 Lee .454 sizing die resolves that problem if you have a reloading or arbor press.

4759 or N110 should work good with 225gr-250gr bullets. The 225gr FTX is a awesome fun bullet and recoil is minimal.