VAhuntr's advice is on the money. All but the most speciality class of "factory" loads are made in bulk. Factory box ballistic charts are nothing more than good estimates based upon load specs and the physics of trajectory. Inconsistency can creep in and the only way to know for sure is to test at the range.

However, to answer your question, a typical 30.06 Spr. load using a 165 gr. spitzer style hunting bullet sighted dead on at 50 yards .... you center the crosshairs in the middle of a deer's engine room, the shot will be lethal. You'll be "off" of no consequence at 100 and a bit low at 200.