I have used them on deer and hogs and with a properly placed shot they normally fold with in 10 yards. Any 300 grain bullet with a jacket is going to do the job with proper placement and enough velocity. All these super expensive bullets do a good job also but dead is dead and they can not improve on that. Personally I like the bonded bullets as I am more comfortable wit long angle shot and bigger game like elk, but I used the regular ones for many years over a lot of game and never had a problem. If you don't place your shot well then it is going to take a cannon with an explosive shell to stop them.