I have been hunting Wyoming for the last 7 years my longest shot was this year 326 yards with a 25-06 at a mule that dropped where it stood. Prevous years I was never over 150 yards for antelope, mule deer and elk. For elk I would use either a 280, 7mm or 308 all have the killing power needed. The 308 is my rifle of choice for Elk the outfitter I hunt with uses a 7mm or 280 for elk.