Start with a bullet you think will work for the game you hunt first. Second slect the powder you think you would like to use. Start at the base load according to the manuals and work up from there with 3 to 5 shot groups.

I use a load from a old 45th edition Lyman reloading book. 150gr bullet and a charge of IMR 3031 powder. It has served me well for 40 years whitetail hunting in Michigan.

Al