I LOVE a 1:48 for Conicals it is my favorite.
370gr Maxi Ball with wad and 90gr of t7 and you will be in buisness.
as far as a rifle if you don't want anything to heavy or long LOOK at the lyman deer hunter or even a good TC renegade, my renegade with the above load has a 2" group and has taken deer out to 125yds with complete pass threws Its an Awesome combo. Also don't be afrade of the patched RB they are killers too.