1:48 is great for patched balls and conicals, even sabots too. The old saying goes, You never know until you try, is exactly the case.
I get excellent groups with a huge 454gr conical in a 1:48 twist cabelas hawken and supposedly those long bullets should not be accurate in that gun. But they are!
Even in my 1:66 twist flintlock i can get hunting group accuracy out to 75 yards with the 245 and 295gr powerbelts.