It all depends on what rifle I am shooting. I do like large all lead conical bullets as they tend to anchor deer for me. I need to put that animal down right now so they do not escape into thickets that are near impossible to drag them back out of. But I also have had excellent luck shooting just a plain old round ball.

I think the answer you seek should be addressed to the shooting situation you encounter. Up close and personal, just about anything should work. But if I were going to shoot some extreme long ranges, from what I have range tested, it would be the Barnes MZ Expander, or Shockwaves.