The one you like shooting the best and are most comfortable with. I hunted with my college .270 ADL with 130 grain cheapo bullets and a $30.00 bushnell 3x9 scope for at least fifteen years and shot a number of elk out to about 350 yeards with no problems. I now shoot a Browning A-Bolt in 300 Win. mag. with 168 grain Nosler hand loads. Doesn't make much of a difference. A heart/lung shot will be deadly with a 30/30.

Good luck!