Based on the moose I had killed in 2006 when this thread was started I would have said the 270 is plenty of gun for moose, even the big Alaska-Yukon variety. In the last six years, thanks largely to the internet, I have learned that no game whatsoever should be hunted with anything smaller than a 500 Nitro Express. Really, what if you're out squirrel hunting and you get attacked by a rabid Kodiak bear that's wearing body armor the anti-hunters put on it. Is that a risk you're willing to take? Not me. Time to go load up some .408 Cheytac. Spring turkey season is about to start.