As a followup on this topic, I talked to the outfitter yesterday and his preference is the 338 in stainless and synthetic stalk. He has a 375 I can use but he feels the 338 is the ideal weapon-gets more consistent expansion. They have had some issues with 300 mag. Unless I decide I want a 338 for other purposes I will take him up on his offer to use his rifle. The reason he prefers the 338 over the 375 is that depending on the hit the 375 CAN blow thru without expanding thus not causing massive tissue damage. In his experience the 338 will always expand well on brown bears and cause massive damage and consequently quick kills.
Thanks for all the input. I am really anxious to go on this hunt. I may have to buy my own gun just to have something to tinker with for the next year. I hear the 338 is a great elk and moose gun as well.