To be very honest... lately, my 100 yard shooting with open sights is not worth a hoot. Because of it, I have decided to limit my open sight shooting now to 75 yards when hunting. I'd hate to wound an animal.
I even was so concerned I went and had my eyes tested by an eye surgeon. He said all was well. But that still did not answer my problems. It seems if I focus on the sight, the target goes blurred. If I concentrate on the target the sights tend to fade. One reason I went to 1x scopes on my rifles when we were not legal to shoot magnified scopes.