I have two favorites. 300 Win Mag and the 270 Win. If I was to choose an all around rifle and only one caliber I think I'd have to take the 270 Win for everything I normally hunt. Which includes up to Elk sized game. It has some of the best down range ballistics for run of the mill factory ammo plus I've already killed everything with a 270 win that I have using the 300 win mag and a lot more of them having the 270 win longer.