Our Biggest Game Animal would be a Whitetail or a Black Bear, we have No Elk or large game so My 50cal ACCURA Inline would be the MLer of My Choice.
Even if it was different, I still hunt with a MLer because I only have 1 shot, that 1 shot has to be placed in the perfect spot to make a perfect kill. So reguardless of what I hunt, big or medium game my 50cal inline ACCURA would still be my MLer of choice. But then you get into what you can and cant use for whatever State you live in so for bullets, powder, scopes, ect so I dont know because I dont have all them regs, we have just whitetails and bear. If I lived elsewhere I'd probably have a different answer.
(BP)