It also depends on how the rifle is sighted in. Center hold, or 6 o'clock hold?
Fact or crap: My very first time deer hunting, I was getting bored. I spotted some turkeys in the valley below (yes, I had turkey tags), and I picked one off at 150 yards with iron sights (rear peep, .308). And I have a witness.
I have no reason to believe MM's buddy couldn't bag that deer at 220.