I shot a legitimate 200+ lb buck with a 80 gr charge of Pyrodex P under a Hornady 200 gr XTP with a Harvester CR sabot. Shot was around 70 yds and he only went about 50-60 before piling up. This is out of my 1:28 GM LRH barrel. I have a .45 Seneca that I am still playing with. I tried it with Maxiball but they were entirely too loose.