BigBore,
I have been eyeing the Bisley .45LC also,I also have two Flat top Blackhawks in .44 mag(shoot great).Everyone I have talked two with the Vaquero/Bisley or Bisley say the shoot great,hold a flater line with the (I will call it the comb) grips,I have a freind that killed a BIG bull elk with his and Buffalo Bore Ammo,almost matches the .454 Casule.

Next spring I might have one,the reason I don' t pick the Vaquero is the fixed sights.BBJ