If I have time and the deer is not aware of me, I will stand for the shot. This gives me the most manuability. If the deer is on me quick or is alert, I will take the shot sitting down. I have an open front climber, making that shot easier. I did have a close in climber and was able to shoot several deer while sitting in it if the deer came in on the left side of me. I practice shooting sitting, standing and kneeling. You never know what type of shot you will get.