There are alot of things to do if you want to properly shoot round balls. Spend some time reading alot of peoples opinions.
First do a google search on how to read shooting patches. When you shoot your rifle you want to walk down range and pick up your patches. There are tricks to reading the patch that can telll you what your rifle is doing. Research and read about it. There is way too much information to write it all down in a post.
More powder is not necessarily better with PRB. Your barrel will only burn so much BP. That is the amount you need to determine.
It does not matter if your rifle is burnig 90 or 100 grains of powder in the summer. You need to be concerned with how much powder your rifle is burning during a cold and wet winter hunt.
For example, your rifle may shot 100 grains and hit the bullseye in July. But if you shoot that same load in December when it is cold and damp then your barrel might only burn 80 grains of powder in the barrel. And shove the last 20 grains out of the barrel. If that happens then your ball will hit lower than it did last July.
This is the main reason most old time shooters in PA use the snow test for testing their rifles and sighting in their rifles. Read about the snow test also.
Join a primitve weapons forum and read some posts. There is a ton of information on those sights. I am a member of "The Muzzleloading Forum". Which is strictly a primitive sight. If you mention an inline or BH powder they will throw you off the sight(exaggeration). There are some real smart guys over there that are more than glad to help you out.
Just be very careful. These rifles are highly addictive. I just bought my second custom MZ. And there is no going back. Tom.