Being sufficient depends on the range you allow yourself to shoot. Up to 75 yds, a PRB is more than sufficient. It can kill out to at least 125 yds with good shot placement. Shot placement is the key.
So, more is involved in the equation than the killing power of the round. I think of using a PRB with open sights. With normal eyesight I believe a PRB is all a hunter needs. It will do all a hunter needs if he's up to taking the shot.
Now, when the range extends. Something more efficient needs to be used besides a PRB. That same more efficient round isn't needed at 75 yds. It's overkill.
Some like overkill. Some hunt deer with a .300 mag when a 30-30 will do fine. Except using a 30-30 means they'll have to be a better hunter by getting closer, and taking a more accurate shot.
If you shoot a sidelock. Good, but why not accept it's limitations? Instead of trying to turn it into an inline with modern power and ammo.
Just my opinion.