I have a 25/06 and love it. I bought it to shoot coyotes and deer. I have even taken several hogs with it also. I can always find the 100 gr core lokt bullets at walmart. I also found a place that has a large supply hornady rounds as well. If there is anything else I want to shoot in the gun it can be ordered online which is no problem either. Mine is a rem 700 mtn rilfe.
Have you thought of a 30/06 with reduced recoil rounds? Just a thought. To speak of something with rounds hard to find my 280 is it. When you do find them they are expensive.
good luck with your choice and I'm sure you will enjoy the 25/06. You might even change your mind on the 300wsm.