Ok, that's different
Barnes 195 MZ all the way in the 45cal SML!!!!!
325gr FTX and whichever sabot yours likes with either Re7, 4198 or N120 at around 2200-2300fps. I use Re7 and N120 for the 325gr FTX in the Savage. Neither is as temp sensitive as 4198. You can get a few more fps but the recoil gets a bit stout.
Start with the low side for 300gr bullets and work up slowly.
Either will slam them and probability of a pass through with good expansion is VERY high even past 200 yards.