The 275s are real good bullets to anchor deer down with. They are one of the powerbelts i had a lot of trouble trying to stop in my sand traps. I sent out around 1,000 of my inserts for the 45 powerbelts and a few thousand for the 50cals, a good number of the 45 shooters used the 275gr 45cal with the insert and were blowing through both front shoulders out to 200 yards. I used the .45 225 on a doe some years ago and the blood trail she left was awesome.