I like the 250 gr bullets for deer I used the250 and 240 gr XTP for many year; Sabot Loader put me on to trying the Gold Dot or Deep Curl as it is called now.
I have used the Deep Curl for 4 or 5 years I use the same 110 gr load with both bullets but since Blackhorn came out I have used only that in my inlines.
The main difference that I see is a properly placed bullet [to me that's on the edge of the shoulder half way up the body] usually drops them on the spot with the 250 gr Deep Curl and most of the time they ran a ways with the XTP.