Both my hunting buddies use the .429 XTP 240 grain non-mag version. They've probably taken 30 - 40 deer with this bullet in the past 10 years. It has worked well for them. I have no doubt that there are more advanced bullets out there, but the XTP does get the job done. The price is right too. I can't remember any instances of bullet failure at with the powder charges they were using (80 - 90 grains T7). Most deer were boom-flops or were recovered within a short distance. Pass-thru's were achieved about 50% of the time depending on a number of factors. There were a couple instances of losing deer or long tracking required - all that I can recall were due to poor shot placement. Again, no matter what bullet you use, shot placement is key.
I have had good luck with the .40 cal 200 XTP, but recently have been using the 200 SST more often.